It wasn't the sort of defeat he was referring to. If it was a one sided fight or a KO then he could forget the big fights, but since it was a good close fight, he's still relevant but needs to win the rematch.
Mayweather may be out of the picture, for now, but Amir still brings hype and generates money, which is what everyone wants.
I still think in England people would pay alot to see him fight Floyd, everyone knows Floyd will school him but we could see another Hagler Minter fiasco