Obviously it affected him but I can't imagine him just not responding if he physically could have round after round of eating punches in the ring, don't imagine him doing much better on a good night. Shane's technique was sharpened by Nazim and his body was able to execute a good performance one last time. Sharp jabs, head movement, combinations instead of loading up on the right hand, good punching technique-with Shane's speed and power, he was able to take all of those things and destroy Margarito. I don't think a level headed Margarito could do anything differently against that, at least not enough to win.
Margocheato has proven himself to suck at the top level without his cement hands...Has he beaten a single ranked fighter since being caught?
he's fought twice, a tune up and against the best he has one more opportunity to show he can do it without the bricks, wish it was someone else besides miguel