Holmes would win clearly and I think could take Bowe out in the later rounds if he really went for it. Also to whoever said Bowe might out work Holmes sorry but that's a load of ****, Bowe had trouble outworking a very bad version of Holyfield and Holyfield still managed to knock him down and nearly take him out. Holmes is on another level.
sorry, what i said was meant to mean that when holmes is on the outiside jabbing bowe, when bowe gets inside/mid-range he should out works holmes there if he expects to win. bowe in the 3rd holyfield was past it, he was slurring his words and almost finished. in his first against holy, he threw 711 punches, very impressive for a big man.
Holmes would win handly if he stayed on the outside and boxed, but if got into a trading match up close (and except for ego's getting in the way, I don't see why it would), it could go either way.