Malignaggi vs Mayweather would be a horrible fight. Floyd would have to be hit by lightning to lose. Khan would have a slightly better chance. Think Khan takes it in a close one.
I liked Khan when he was with Freedie.... he is a good offensive coach. He left him because he needed more defence but as you saw in Khan's fight with Diaz... it's not defence that he needs. With Virgil Hunter, Khan is more of a thinker and it takes away from him speed which would catch the opposing fighters off guard.