Hopkins will catch Calzaghe with those lead rights at least once per round. Calzaghe will win the fight though.
Hopkins vs Jones was in 1993. I don't think it has much relevance now. Heck, Echols II was in 2000 which was 8 years ago now.
I just get the feeling that Hopkins is going to tag Calzaghe plenty of times with his withering right hand leads. Calzaghe has never faced someone as crafty and intelligent as Hopkins. He will learn a few things.