I think Wright has very good chance against Floyd. Wright also would've beaten De la Hoya at 154. Mosley and Trinindad looked completely helpless against prime Winky.
Floyd was pretty good vs south paws and if he took wrights jab away could he be effective? Floyd was very versatile and mobile. could wrights defensive shell be enough to totally nullify Floyd? I don't know
The only "nightmare matchup" I can think of for Floyd is Tommy hearns. I don't see why Floyd wouldn't just outbox winky
Mayweather would be to fast for him. That arms up shell defense of Wright works best on slower less skilled fighters. In Mayweather we're talking about an overall better skill fighter with a lot more speed and quickness than Wright. Mayweather by comfortable decision.
"Prime for prime" isn't possible with this one. Winky never fought at 130. Unless you want us to consider a teenage Winky that we never saw fight?