Salido and Teo could not beat Roman Martinez and Kambosos. While Lomachenko beat one of them and will beat the other very soon.
It's a 50/50 fight that I'd slightly lean towards Mayweather due to his size. Eventually, the reach disadvantage becomes a bit too much as well but no shame in losing to one of the very greatest in Floyd Mayweather Jr. However, time will tell and I may change my pick depending upon how Lomachenko's career looks like after he retires. But the one thing that is not going to happen, is either guy schooling the other. Nobody schools Lomachenko, not even Floyd.
Mayweather would adjust and figure out a way to win. Loma is great but you would never see Mayweather vs anyone take as long as Loma did vs Teo to adjust and change the course of a fight. Mayweather may be a lot of things but in the ring it can't be denied his boxing IQ is top of the tree.
I think some people need to go back and watch Mayweather at 130 and 135, and then come back with a more realistic and balanced conclusion. Loma absolutely does not, in any way, have the upper hand against PBF, not even offensively at those weights. I rate the guy but I can't see anything better than an 8-4, 9-3 kind of loss. Even just looking at the last 20 years, I can't favour the guy against Pac either, and Oscar, Crawford, Mosley, Barrera and Morales would give him hell.
Lomachenko is significantly well more rounded and skilled than Mayweather. The " but Mayweather gots the ring IQz" saying is just that, a regurgitation from what commentators have been feeding the fangirls over the years. The only advantages Mayweather has over Loma is size and reach.
Lomachenko lost to a straight B fighter (who had natural physical advantages, but not so much as to represent an inherently insurmountable task for a guy of Lomachenko's size). He isn't beating Mayweather on any day of the week.