I don't know if this will negate it but I would recommend left hooks to the body and go for more bodyshots than headshots as the shoulder roll is designed to make the left side of the orthodox fighter look open then you go for a straight to the head and get nothing.
man... every time i hear floydshoulder roll, ellerbe rolling his hands on floyds shoulder just pops into my head. somebody please shoot that maggot.
The “L formation” or “Kronk Defense” is part of Floyd’s system. The right hand is held high to parry jabs and block hooks while the left hand is held across the belt line. The chin is tucked in behind a shrugged left shoulder. Floyd uses this stance to invite your right so that he can roll back and counter with his own right. Set a trap: feint the right and then whip a left hook so you can catch him throwing his counter right. He also has a habit of bending at his waist and to his right. The cure is simple: Shoot a left cross at his heart or at the cusp of his left deltoid. Get close, feint the right, and as he bends to your left, shift your weight on to your front leg and leverage short left hooks and hybrids, mixing in short rights and right hooks to the body. http://www.thesweetscience.com/boxing-article/6682/blueprint-how-beat-floyd-mayweather/
Can't be that simple or 39 different guys in five different weight classes, somebody would've gotten the SOB by now.
They fight somewhat alike. He uses the shell defense shoulder roll in which the thread is talking about. I know this is just one of Mayweather's methods assrod.