Bowe and Tyson were both undisputed champions, Golota was never that great to begin with either. Ike on the other hand could have really made it, but he is a nutter, so he didnt.
No one mentiones Vitali? As much as I do not like his style, he could have probably cleaned out the division (with the exception of Lewis). Or at least he could have tried. Instead he finished his career with great wins over not so great opponents, and losing to the only top fighters (two) he met. And still the loss to old and out of shape Lewis seems to be his biggest achievement...
I would argue that we can never know the biggest waste of talent because the truly worst waste of talent probably never even made a dent in the pro scene
Ike gets more hype and awe from fans now than if he'd actually kept fighting. It was only a matter of time before he was exposed as a one-dimensional swarmer. That he left "on top" is the biggest reason the myth keeps going. He gets HOF hype with a contender resume. It's a shame he didn't get help for his issues, but then the question becomes...is a sane Ike even the same fighter?
Tyson could have been probably the GOAT. He was great when he was young, just think about it, what he could've been, if he would've improved and be better than, when he used too be Iron Mike Tyson, he would be the Greatest.
Marvis Frazier? He had a great amatuer career. He was a highly touted prospect and among the top ranked amateur heavyweights. He was the 1979 National Golden Gloves Heavyweight Champion and 1980 National AAU Heavyweight Champion. Among his victims was future pro contender Mitch Green, and future champs Tim Witherspoon, and Bonecrusher Smith. He was KOd by James Broad. But his pro career was a disaster. He could have been a great boxer not a puncher.