Mayweather's clearing out the mma-boxer-crossover division. Can't think of anyone else. Does that count?
When Ward was in limbo, the guys he beat all won and held titles. Abraham had the WBO Froch with the IBF And Bika snatched the WBC. The only guy Ward missed at 168 was Bute.
Think it's very difficult really 'clean out' a division, that basically means you've beaten every contender worth fighting in the division. There's always some new up-and-comer who wants a piece or some other titlist you haven't fought. Mayweather at 130? Tszyu at 140? Ricardo Lopez at 105? Even guys like Calzaghe (Ottke) and RJJ (D-Mic) can't really say they did it as there was an undefeated rival world champ throughout most of their reigns. Ward is arguable, there was a big Bute-shaped elephant in the room, but then Froch went and dealt with that one for him...
Hopkins cleaned out 160 at one point, but lingered too long and got beat (albeit controversially) by a new contender, does he count?