Well yeah, that's a good indication that you were using your calves to try and get power... but that's not what calves are designed for. They are for stability and as someone else mentioned they shorten very little during jumping/running/punching etc. Biomechanically they aren't made for generating power, what your problem then was basically bad technique/incorrect motor patterns ingrained into your style of fighting. Cramps/injuries are always a good indication that you're not doing something right biomechanically speaking. If you ever did isolation exercises for your calves you'd only worsen the problem, and you do have well developed calves. It's the tendons recoiling from the work done on them by the larger muscles higher up that generate power, the calves need to be strong isometrically to pass that rubber bands momentum into the feet and ground. At the highest speed part of the movement when the foot is exploding into the ground the calves need to be stable, those muscles are very slow compared to the tendon snapping back. The more you're using your calves to generate power in your punch the less you're utilising that elastic energy, hence the less power you generate.
calf muscles are very much genetic but also being on your toes quite a bit helps build the strength and muscle. Pac is always bouncing around
I also have massive calves and I used to be a high/long jumper back in high school. I used to be in tae kwon do in college to and this calves made me move a lot. and i used to be in labor camps when I was a kid that's why I developed muscles early.
I think that the external and internal oblique abdominal muscles can help u to punch hard too , especially when u throw hooks. http://www.medicalook.com/systems_images/Muscles_of_the_Abdominal_Wall.jpg shoulder and lats too
This is actually a good point. Larger cells are less efficient. You can probably grow extra capillaries to compensate, but probably not quite enough.