Floyd was also catching Zab's jabs out of his high guard. He's shown before that he can block southpaw jabs out of his "usual stance" with his left forearm. Since when was pakayo a jabber? Zab gets his gun off faster than emmanuel pacman, and even Floyd himself. The special thing about manny the southpaw is that he actually has a right hook in his arsenal which is something missing out of too many southpaws. Right after Mayweather rolls off that punch it makes it easier for him to follow up with "his favorite" punch the one southpaws are most vulnerable against, and it's the same one the too slow to generate pop Clottey was able to land. Anything a southpaw does to an orthodox fighter the orthodox can do back to them. A straight left or right is usually the best punch vs someone in a different stance. Both fighters have great straights, but Mayweather has the better one. He was already able to triple up on it as a young 20 year old kid; that's how he KO'd one of his southpaws. We rarely even see a seasoned and experienced veteran double up on it, let alone triple. An exclusive disadvantage to southpaws against orthodox fighters is that their liver is closer to the orthodox fighter's lead head. PBF has landed the rare straight right to a liver before to get a KO win. It'll be a hard fight for emmanuel pacman even if Mayweather doesn't do all of his usual tricks against southpaws. Roach, who knows pac better than any of us, believes the pac would need to fight the "perfect fight" against Mayweather, despite his thinking that Mayweather doesn't like southpaws. Will be interesting to see how the pac reacts to being in the ring against someone with faster hand speed, better footwork, superior timing, much moar agility, and a straight that's more versatile.
Timing is the answer to speed. Mayweather has some of the best timing in boxing. Add Mayweather's speed to his timing. Unless Pacquiao can get to Mayweather early. I don't see how he beats him.