Khan's highguard and straight down the middle fast punching will expose alot of U.S boxers based style. The low left hand lead will get exposed by Khan due to his great jab, highguard, reach, and speed around 140. Khan finds and uses range to a great effect.
Pacquiao has better footwork/handspeed than Khan and was still caught a few times by Cotto. I remember a particularly murderous uppercut. Khan will be clipped and his chin is very weak. Against a concussive puncher like Cotto I couldn't see him making round 8.
Roach himself has said Khan has faster handspeed than Manny. On to the Cotto vs Manny, Manny got caught because he closes the range and wants to fight thats his style, Khan wont fight Cotto, he would try to box him at range this would be the plan. Still its a 60-40 to Cotto in this fight because Khan at real world class level is yet untested.
Khan has actually a pretty solid amount of pop behind his punches. His KO record is obvious proof of that...
Cotto punches too hard. He would KO Khan. The only people to beat Cotto are those who were extremely offensive and would stand and trade punches. If Khan did that, he would be knocked out, if Khan dances around and jabs all night, he has a slim chance of getting a decision but I couldn't see him go that long without Cotto landing a few clean shots on that dodgy chin of his.
The last thing Cotto needs is to go against elite level speed and in this case one with a lil bit of pop to it as well.