Does a third fight happen next? I highly doubt it, but does it happen sometime in the future? I think its possible. I'd imagine Cotto is very high on the list of guys who face Mayweather or Pac if they don't face each other next. I'd also guess guys like Chavez, Alvarez, Ortiz-Berto winner would all be possible options for Cotto. He has a number of big fights to choose from to keep him busy for a fight or two. But if Cotto goes on and loses in his next fight or two even and Margarito rebounds with a nice win or two of his own over guys like Mayorga, Wolak, Martiroysan, etc than a third match becomes pretty attractive. I don't think Cotto has any use for Margarito at this moment and would probably tell you a third fight never happens, but if things break the right way then a third match becomes possible.