Not a chance, not agile enough, hand speed means nothing if you're not in a position to land. Plus Ruiz has always been far too easy to hit.
You didn't read the thread title. The Ruiz who got out boxed by Joshua in the rematch, struggled with Arreola and drew with Miller was NOT fit. Far from it in most of those examples. Particularly against Joshua.
Joseph Parker and Anthony Joshua comprehensively outboxed him on the back foot, and that's not even their forte, Usyk is a master at it and a southpaw. Speaking of which, ancient southpaw Luis Ortiz if it weren't for the knockdowns, would have won unanimous decision. So in short, Fat Andy doesn't stand a chance.
What is the difference between Andy Ruiz and Bigfoot? One is an enormous, frighting, 800 pound monster. And the other has big feet.