Duran (of the Barkley fight) vs Mayweather (of the Pac fight)

I think that entirely depends on how much he respects Mayweather's defense and how effective of a counter puncher he is. My thought process is that Duran doesn't have the work rate or stamina to throw enough punches to win this fight, because he won't be landing 1 in every 2/3 punches he throws. No matter how precise of a puncher he was, I can't complete discredit his opponents biggest strength and because of that the most likely scenario I envisage is Duran being gun shy for portions and even a little frustrated.

Prime for prime is a completley different kettle of fish though.