I mean from a purely physical perspective, Manny is going to hit you with more combos, throw more, quick and with a knockout on his mind...so in terms of next-morning hangover you'll probably feel worse from such than from 12 rounds of pot shots (even pinpoint flush counter rights) - but it must be pretty embarrassing to miss the way Floyd can make people miss, repeatedly, in front of a crowd.
Rather get beaten by Floyd. Id take a dive at the first jab. Mannys first jab would likely be a Manilla Ice