Which boxer had the best genetics? One genetic freak was Mike Tyson, just look at how he was built at 13!! https://img-9gag-fun.9cache.com/photo/aZ0LBvW_460s.jpg
Pacquiao's legs were something else, that buzzsaw never stopped once before 2012 when the power of the pee finally prevailed.
Ali and Foreman were both freaks in their own way. SRR as well. To be able to do some of the things they could was pretty special.
Roy Jones Jr. The man could probably close his eyes, trust the force and pluck the wings off flies as they buzzed by. His reflexes were from another planet. The best of physiques have six-pack abs: Roy had an eight-pack.
How would you even know, for the most part? Most contenders probably have genetic gifts, but they're also the product of training. When you get to the level of elite boxers, most of them are already (probably) going to be born athletes from the get-go. You're trying to distinguish the genetically gifted from the super-genetically-gifted in a sport where many athletes keep their training relatively private. Tyson is abnormal, yes. But young Cleveland Williams was also knocking adults out. (Actually looked a bit like Tyson, come to think of it.) Jimmy Wilde was allegedly beating up adults in a boxing booth as a kid, and he was tiny even as an adult. Etc. The only guys I can immediately think of with verifiable genetic gifts/abnormalities would be Carnera and Valuev. Hank Armstrong allegedly had an abnormally slow heart beat even by athletic standards, but he might just have been a *merely* gifted athlete who worked out like the Dickens.
I noted that in another thread on lookalikes. Compare this to the photo the original poster added. There's another shot of Cleve smiling, showing a gold tooth. Even details like that, and the little parting cut into his hair. Uncanny resemblance, like Haugen and Greb. https://photos.com/featured/cleveland-williams-the-stanley-weston-archive.html
But I think my answer would be Liston. How the hell could a child grow up in that environment, one of 25 with not much food for more than a few, and yet have that upper body? It was like a barrel of muscle. He can't have had a full meal until he was in St Louis in his mid teens, surely.
I mean, the gibbon arms are just weird. His wingspan was like one of those party horns that just keeps unrolling.
Mike "Hercules" Weaver was very muscular. Maybe he used PEDs (especially in his later fights) but I think he was naturally gifted too. Nicolino Locche (El Intocable) was a smoker and I heard he did not train as much either. His punches were rather soft but his natural reflexes were out of this world.
Saad Gatti Chuvalo and Cobbs ability to absorb punishment and keep on fighting on 8 cylinders not to mention Battling Nelson and Ade Wolgast