Honestly I still think that Manny will beat his ass regardless of his size and power advantage but Margo cornering him is not impossible.
If he wins, it'll be because of the weight. Pacquiao may not be able to keep him off him for 12 rounds or force Margarito backwards, and if Margo keeps taking the shots and throwing them back, he could be in trouble. I'm sure he won't be, though. The two things in Margo's favour is he will always keep coming and I think he punches a lot harder than Pacquiao, especially as a Middleweight, I imagine.
Oh no I wasn't saying he won't as in he won't corner him. I was answering the question of how will Margo beat him. :good But I honestly don't think he'll corner him either, unless Pac lets him. Yes LETS him. :yep Not impossible though.
It's hard to say how Margarito would win, he's slower and his defense is not that great. But this is boxing and he is the bigger between the two. All it takes is one good shot to spoil either one of there nights. I have Pac beating him, but stranger things done happen.