How would Prime Mike Tyson do against these fighters in their prime?

This. Foreman was so open all the time, Mike wouldn't have missed a single shot. The question is how many punches can he take before he falls down

 

You've got more guts than most here b/c Tyson is almost as worshiped by many here as Ali is.
I think he does somewhat better than that, but not much better like win most of these theoretical match-ups.

 

Haye sure. I can say with absolute certainty that it's far from absolute certainty he defeats Wlad or Wilder.

I give Tyson the nod over Wilder, but if Douglas can stop a young Mike, one clean landed right by Wilder would put Mike in serious trouble. Pre prime Wlad likely (not a sure thing) losses. But the Wlad under Emanuel who mastered jab, grab (as good as Ali), with that left hook/jab, huge right cross after rounds of jab & clinch very likely defeats Tyson.

 

Loses to Foreman
Loses to Ali
50\50 with Holmes
Beats Bowe
Loses to Lewis
50\50 with Vitali
Beats Wlad
Loses to Fury
Beats Haye
Beats Wilder
Beats Holyfield