The real question is: how many Marlboros will Mayorga smoke on the day of the fight, and how many Buds will he drink?
Not sure about a KO, but Shane doesn't lose this fight. Keep in mind Mayorga's chin is a rock as long as he sees the shots coming. I'm not sure I've seen Mosley throw a series of fluid combinations in about six or seven years. Possibly an attrition type KO or ref stoppage late if Shane is teeing off with free shots.