I'd dump my life savings on Iron Boy with zero hesitation. Chihuas runs extremely hot & cold - and even at his very best Rodríguez would be in with barely a whiff of a puncher's chance, and that's without even factoring in that light fly wasn't his optimal weight. Even a halfway-shot Calderón would soundly outbox him IMO. Drag the boricua up to super fly, and make it the highly motivated version of the Mexican that fought Ioka, then yeah - flip the script and you've got your KO following more or less the Segura blueprint. Down at 108lbs, however - nope.
Split the difference making it 112, and it gets interesting. Purely conjectural though as one guy never fought that high.
Prime Calderon would get this done at a canter, no matter how hot Rodriguez is running IMO. He was absolutely sensational at his very best and doesn't get his due IMO.
See Nietes-Rodriguez. Rodriguez makes it a bit uncomfortable for Ironboy at points, but can't pin him down long enough to do any meaningful damage or to win any more than three rounds at most.