I'd love to be able to say yes, but with all of the heart in the world, the sheer size of both Klitschko's and Valuev etc.. he would struggle purely because of the size.. if the men were guaged on ability only and the weight (size) diff was level, Jerry and his massive heart wins every time.......
Quarry is one of the best HW who never won a title. He would be too small against todays super heavys, but he would tear hell out of the cruisers.