I would say the early rounds is where Mayweather is at his most vulnerable, because those early rounds is where Mayweather tries to work out his opponent and thats usually where he gets hit with something big. Judah dropped Mayweather in round 2 Hatton almost dropped Mayweather in round 1 Mosley landed THAT shot in round 2 Maidana landed THAT shot in round 3 dont be surprised when Pacquiao drops or even stops Mayweather early on in the fight