I've always wished there was a boxing/combat sport that allowed one vs multiple to see how feasible this was. I'd guess Tyson could do it, but we can't be sure how difficult it would be against two other pros at the same time. If anyone could, I think Tyson's skills translate best to that.
These two opponents, yes. Seeing as Mark Young seemed to go out without getting hit, I think Tyson would do fine here.