Mayweather stumbled over Hatton's foot. Anyway, currently I'd say Rafael Marquez has one the most, if not the most, powerful jabs today. He staggered Silence Mabuza with it in their rematch, and from the looks of it, it was originally a jab that broke Israel Vasquez's nose in their first fight. His jab sounds like a power shot.
As often mentioned the power to weight ratio decreases as weight increases so there is no way it can be a heavy weight. All time I'd go for holmes. Also fighting orthadox as a natural left hander is cotto with a good jab. Wlad is probably the most effective jabber but p4p not the most powerful.