Cotto showed great boxing skills, good movement and accurate punching all night but Margarito took everything Cotto could dish out and was relentless as always ! The thing with Margarito is that it's abnormally draining to fight him for 12 rounds if you're smaller, no matter how great your conditioning and skills are... Floyd would have swept the first 6 rounds easy on skills alone but he might have been in trouble once the 10th-11th and 12th rounds came up ! Margarito will always be a risk for any elite fighter at 147, no matter who they are !!
I dunno, Floyd unlike Cotto wouldn't tire out. I think he'd likely pot-shot Margo all the way thru 12 rounds like he did against Baldomir.