Spence's ko's end here. He has entered the top echelon. These guys wont be taking flush shots all night like brook(who was stopped to due a broken socket from a headbutt anyway). If he wins it's by decision. Against pacquiao he'll be trying to box again. Pacquiao will be much faster and more powerful of hand and foot than mikey so it should at least be more competitive.
Yeahhh I'm not to into this one personally, altho it looks pretty likely to happen sometime in the near future. In all likely Spence fights a similar fight to the one against Garcia and looks to either finish it late or win a commanding UD after dominating the rounds off the jab and his size/reach, power, athleticism/def. Unless Pacquiao decides to go full Kamikaze then it ends in a KO.. Most probably Spence by wide UD.