Ponomarev is a very solid fighter and he's definitely no mug. Problem is he lacks power and if he fights Spence the way he does in the fights I've seen of his (which admittedly is only 2 or 3) I don't think it will be good for his health. I say that because he is tough, determined and gutsy and he won't go down without a real fight. If he could punch I would give him a much better chance.
Spence. Ponomarev is 23 years old and has been making improvements, but the Spence fight is too much too soon. I fear for Ponomarev's health in this one. Hope it doesnt happen :shrugs
Vasquez is going thru the WBC route. I guess he could fight Berto v Ortiz winner for a mando position at DSG's belt.
It'll look very similar to the Algieri fight. Solid, resilient, decent movement, no power. He's just not elite level, at least not yet. KO6.