Ketchel destroyed clever fighters a a rule, O'Brien, Sullivan and Kelly were all taken apart at the seams. McCoy has exceptional rugedness, too, he was not exactly what you would call vulnerable, but based on the styles I think you have to go with Ketch.
from what I've read on the two fighters, I too would go with Ketchel. It's a same his life was cut short.
Going to go with Ketchell at middleweight, but McCoy has a verry good chance. McCoy is the more proven of the two at heavyweight. Ketchell has the better results vs common oponents at middleweight and light heavyweight, although McCoy is on the slide by the time he meets these men.