I'm one of the few who favors Oscar De La Hoya at any stage of their careers. He holds significant physical advantages over Chavez, and this coupled with his tremendous hand speed, solid punch resistance, and punishing jab would make it all very difficult for Chavez to overcome.
135Lbs Chavez smashes Hoya in the tenth round. Chavez could cut off the ring way better than Tito and would finish him off with a similar body punch(but real) to the Hopkins body punch.