If he lands the big shot, my dog will be the next pope - all in accordance to axiomatic mathematics: if the assumption is false the implication is always right. Seriously though - I believe he can take it. It should be interesting to see how he reacts to it though. Especially if he gets into "panic mode".
No. It will take more than one shot. Wlad clinches, gets separated, then clocks him with the jab and goes back to outclassing him before the inevitable TKO.