What is the best spot on someone's face to punch in order to knock them out?

You can't say it in general as everybody is reacting different.

One is going down from a big shot to the temple but can take shots to the jaw and the opposite.

 

Temple is the worst/best spot to land.

 

In the spirit of the game just a well timed punch to the chin take some some beating,quite often it’s the grey area of behind the ear that really **** folk up.
Temple area apparently is horrible,remember those top of the head Golovkin shots,those that Fury took just scrambled him instantly.

 

whichever part is going to twist their neck around , usually the point of the chin (from a hook)

 

Yes which must take some doing as we don’t see this all the time,Amir Khan has to be the best....”ok mate you just stick your fist out there and I’ll run onto it at speed giving you highlight of the decade lol.
Some of those Khan knockouts I’ve seen in slowmo and you can see a ripple effect from the chin upwards.

 

Aim for the mouth.

 

I don’t know. Tszyu just tapped Judah on the kisser and made him doing the drunken dance.
Green just graced Roy’s temple and got scrambled.

 

Roy is far from having a bad chin. Roy has a better chin then 99% of all those monkeys here. You do not become a 4 weightclass champ with a horrible chin.

 

What. In boxing terms, Roy’s chin was not good. Post prime, his legs turned into jelly just about everytime he was solidly hit.

 

Yeah because boxers have in general extreme good chins. I would bet a 10k that you and me would kiss the floor from every power punch that lebedev threw at him