Corrales because of the way he beat him even though most people recognize Corrales wasn't at his best in that fight he was highly considered at the time.
His total domination of Diego Corrales. At the time Corralea ws undefeated and knocking guys out. He took Chico apart knocked him down and out. I would never see that Mayweather again.
The biggest name on his record by far is Oscar De La Hoya obviously, however his best performance and therefore probably best win as people have mentioned is probably Corrales.
I might have to agree with Chico. He gave a boxing clinic against an elite fighter at the time, but DLH is the biggest name for sure.
I agree to some extent bro...[he was going thru hard times] But that still has zero to do with Mayweather. Floyd can't control what Diego does on the ouside world. If Diego was so out of it, maybe he should have cancelled the fight. A peak Floyd showed up to fight that day.
the question asked is what is mayweathers biggest win: oscar best performance imo was against gatti, i believe that victory got him the p4p title???
DLH was the biggest name. I wouldn't consider it a career defining win. I rank his win over an undefeated hatton as a big win at the 147 weight. he had many very good wins at the lower weight.