Loaded Gloves. Guys take PED'S to improve stamina and strength. PED's can't give you skills like a great jab or great right hand but Loaded Gloves can do some major damage to guys.
Using loaded gloves is like bringing a gun in a sword fight. PEDs would be like Popeye eating spinach for a fist fight. They're about the same.
PED's can work against a user just as easily as it can help. It would be near impossible to get consistent results in such a mental sport. Loaded Gloves are guaranteed one way destruction and disgrace meant to inflict criminal harm. When removed it can work against a fighter as with Margarito in the Shane fight. The less on a fighters mind the better he will perform.
PEDs allow you to train harder and to train more. Better training means better skills. But loaded gloves is really dirty.
This is kinda a no brainer...Of course loading your gloves is far worse than taking PED...PED doesnt ensure you a victory like a loaded gloves would.