the first few that come to mind are: anderson silva hector lombard and former HW champ and now fighting at MW - vitor belfort. also dan henderson i would put these guys in with anyone and anything can happen.. all of them have the skill, experience and punching power to KO anyone! would you agree?
ok we know belfort can bulk up to a healthy weight at HW and he has legit power and chin at that weight so why not? silva isnt an easy guy to find and im sure he has enough power and skill to beat them guys not to mention a pretty good reach. dont be deceived by the weight. lombard is another version of igor, maybe better grappling and more technical boxing with thunderous power in both hands. apparently he had wars with barnett in the gym so it shows he can hang with the big boys. dan henderson has fought heavyweights before, the nog bros, fedor and more. he has skill and 1 punch power. i dont know about JDS but overeems chin has been cracked by a light heavyweight before, why not again?
Guys who can transcend weight would include those. I'd figure Jon Jones could **** some guys up at hw. I would have to believe that these guys would lose to the very best heavies i.e. JDS, Reem and Cain.