From the 2 examples you mentioned, then easily Paul Williams, I've suffered a fractured orbital bone before and the area can be sore for a very long time, **** knows what Tony musta been feeling yo.
Probably beaten up for 12 rounds... I'd prefer to be Paul Williams rather than Antonio Margarito though. What a jabroni.
Knocked out. Probably less long-term damage despite the greater single shock made in a KO, less pain both short and long-term, and I think I'd feel less bad about "getting caught" then about having no answer to a beat-down for the course of a whole fight.