He certainly has a chance. Both brothers are there to be beaten they're not invincible. If Chambers sticks to a gameplan he could definitely win. Whether he has enough power to KO Wlad is debatable but I would give Chambers a good chance at winning on points.
Chambers is going to get crushed. This is like Wlad-Brock II, but probably worse for Chambers, honestly. I like Eddie but he's not big enough and doesn't hit hard enough.