Cotto outclasses him as long as he stays away from that right hook. Which I'm not exactly sure he could with 100% confidence. And that is more testament to how good Lee is to pull that right hook trigger. However, I would easily favor Cotto to control the ring generalship, footwork, distance etc. All Cotto outside of the right hook icing. So its always a toss up right now with all of Cotto's fights at 160lbs. Hes a small dude. But game.
Lee is a second teir fighter in comparison to Cotto. Unless Cotto suddenly loses it he should beat Lee via late ko in an exciting fight.