Wladimir has power in both hands.. I wouldn't bank money on most heavys thru history standing up against an onslaught with either hand..
I think Id give it a shot if there was some money in it, I`m 245lbs. and I'm a south Paw. If I landed flush on that chin then I just might be able to pull it off. Dont forget its alot easier to see punches coming when its only coming from one side. If he started using his left I would give myself 1 minute of survival time unless I just kept running away.