The punches you don't see hurt the most, Tyson loved to "make 'em miss, make 'em pay", with timed bombs countering the punches thrown by his opponents at the super-elusive target closing rapidly upon them. A counter lefthook, followed immediately by more supersonic, devestating nukes may just close the show. However, more likely is that the ref saves a battered Chuvalo against the ropes, to stop Tyson unloading further lethal combinations.
Of course he could. Nobody is that infallible and if someone like Tyson could not only catch you right, but follow it up with a serious of hurtful punches, then in all probability you will be kissing canvas.